Skip to main content
. Author manuscript; available in PMC: 2014 Jan 10.
Published in final edited form as: Circ Cardiovasc Interv. 2013 Nov 12;6(6):701–709. doi: 10.1161/CIRCINTERVENTIONS.113.000195

Table 3.

Histomorphometry and Histology Results at 28 Days

Control Nab-Rapamycin PValue
Quantitative analysis
 Lumen area, mm2 1.9 (0.85–2.6) 2.6 (1.8–3.3) 0.04
 Percent luminal stenosis 17%(12–35) 10% (8.3–14) 0.001
 Neointimal area, mm2 0.38 (0.19–0.57) 0.26 (0.22–0.32) 0.04
 Neointimal thickness, mm 0.16 (0.096–0.37) 0.096 (0.081–0.19) 0.02
 Medial thickness, mm 0.51 (0.41–0.53) 0.45 (0.37–0.53) 0.63
 Intima/media ratio 0.13 (0.087–0.21) 0.099 (0.088–0.14) 0.05
 Total vessel area, mm2 6.8 (5.0–7.3) 6.6 (5.7–8.0) 0.1
 Adventitial microvessels 15 (9–22) 7 (3–10) 0.001
Semiquantitative analysis
 Injury 1 (0–1.5) 1 (0–1) 1
 Inflammation 1 (1–1) 1 (1–1) 0.6
 Medial fibrosis 1 (1–2) 0.5 (0–1) <0.001
 Fibrin/thrombus 0 0 0.6
 Hemorrhage 0 0 1
Pigs (femoral injury sites), n 2 (4) 2 (4) …

All values are median (IQR). Pvalues are from mixed-effects linear models (see the online-only Data Supplement).