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. 2013 Aug 1;7(8):1–9. doi: 10.3941/jrcr.v7i8.1470

Table 1.

Summary table for nonketotic hyperglycemia

Etiology: Controversial, leading hypothesis states hyperintense T1-weighted signal is secondary to unwrapping of myelin sheath and swollen gemistocytes [3,5]
Incidence: Rare; largest published case series consists of 53 patients, majority of reported cases involve Asians [2]
Gender ratio: Of the 53 cases with gender available, 30 females and 17 males (ratio of F to M: 1.76) [2]
Age predilection: Range: 22–92 years, mean age of 71.1 years [2]
Risk factors: History of poorly controlled diabetes mellitus [2]
Treatment: Normalization of blood glucose levels with appropriate insulin therapy [2]
Prognosis: Excellent with timely instillation of insulin therapy [2]
Findings on imaging: MR: unilateral or asymmetric T1-weighted hyperintense BG lesion, T2-variable, susceptibility and diffusion - variable, often enhances [2]