Etiology: |
Controversial, leading hypothesis states hyperintense T1-weighted signal is secondary to unwrapping of myelin sheath and swollen gemistocytes [3,5] |
Incidence: |
Rare; largest published case series consists of 53 patients, majority of reported cases involve Asians [2] |
Gender ratio: |
Of the 53 cases with gender available, 30 females and 17 males (ratio of F to M: 1.76) [2] |
Age predilection: |
Range: 22–92 years, mean age of 71.1 years [2] |
Risk factors: |
History of poorly controlled diabetes mellitus [2] |
Treatment: |
Normalization of blood glucose levels with appropriate insulin therapy [2] |
Prognosis: |
Excellent with timely instillation of insulin therapy [2] |
Findings on imaging: |
MR: unilateral or asymmetric T1-weighted hyperintense BG lesion, T2-variable, susceptibility and diffusion - variable, often enhances [2] |