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. 2013 Oct 17;105(22):1677–1683. doi: 10.1093/jnci/djt282

Figure 1.

Figure 1.

Examples of qualitative interactions. Gefitinib vs carboplatin + paclitaxel for first-line treatment of non–small cell lung cancer patients with EGFR mutation–positive tumors (A) and EGFR mutation–negative tumors (B) [adapted from Figure 2 of Mok et al (11). Reprinted with permission. Copyright 2009 Massachusetts Medical Society.]. Cetuximab + chempotherapy vs chemotherapy for first-line treatment of non–small cell lung cancer patients with high-expressing EGFR immunohistochemistry (IHC)–positive tumors (C) and low-expressing EGFR IHC–positive tumors (D) [adapted from Figure 4 of Pirker et al. (13). Reprinted with permission. Copyright 2012 Elsevier]. PFS = progression-free survival.