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. Author manuscript; available in PMC: 2014 May 14.
Published in final edited form as: Cell Rep. 2013 Nov 7;5(3):654–665. doi: 10.1016/j.celrep.2013.10.007

Figure 7. SIRT7 rescues high fat diet-induced fatty liver.

Figure 7

Data shown are comparison of livers of mice fed a chow diet, a high fat diet, and a high fat diet with SIRT7 reintroduced specifically in the liver via AAV8-mediated gene transfer.

(A) Quantitative PCR analyses for gene expression of ER stress, inflammation, and lipogenesis.

(B) Western blotting for ER stress markers.

(C) Morphology.

(D) H&E staining, Oil Red O staining, and F4/80 staining.

(E) Quantification of liver triglyceride.

(F) A VLDL-TG secretion assay.

n=6. Error bars represent S. E. M. **:p<0.01. ***:p<0.001.