Table 1.
Baseline characteristics of cases and controls
| Variable | Controls (n = 46) | Cases (n = 23) | P-value |
|---|---|---|---|
| Age (years) | 57.8 ± 8 | 58.2 ± 10 | NS |
| Female | 23 (35%) | 6 (26%) | NS |
| Smoking | 32 (52%) | 11 (50%) | NS |
| Diabetes | 6 (9%) | 5 (22%) | 0.06 |
| Prior MI | 8 (13%) | 7 (30%) | <0.01 |
| HTN | 30 (48%) | 14 (63%) | 0.08 |
| BMI | 27 (24–27) | 30 (25–32) | NS |
| TG (mmol/L)a | 1.0 (0.66–1.7) | 1.7 (1.0–2.2) | 0.05 |
| TC (mmol/L)a | 4.3 (3.9–5.4) | 4.4 (3.8–5.3) | NS |
| HDL (mmol/L)a | 1.1 (0.9–1.8) | 0.9 (0.8–1.0) | <0.01 |
| LDL (mmol/L)a | 2.6 (2.2–3.3) | 2.5 (2.1–3.4) | NS |
| BUN (mmol/L)a | 4.3 (3.2–5.7) | 6.4 (5.0–7.9) | 0.05 |
| Cr (μmol/L)a | 82 (70–88) | 88 (82–106) | 0.05 |
| SBP | 133 (120–150) | 130 (115–150) | NS |
| DBP | 73 (70–80) | 70 (60–80) | NS |
| EF (%) | 65 (62–66) | 40 (35–45) | N/A |
Continuous variables are presented as mean ± standard deviation if normally distributed and median with interquartile range if skewed; categorical variables are presented as frequency and percentage.
BMI, body mass index; BUN, blood urea nitrogen; Cr, creatine; DBP, diastolic blood pressure; HTN, hypertension; MI, myocardial infarction; N/A, not applicable; NS, non-significant; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides.
aSI measurements. To convert to mg/dL, multiply TG by 89, TC, HDL, or LDL by 39, BUN by 2.14, and Cr by 0.011.