Table 1.
Demographic characteristics by era
| Era | Era 1: pre-CNI (1963–83), n = 114 | Era 2a: CNI + steroids (1984–99), n = 262 | Era 2b: steroid-free CNI (1999–2011), n = 77 | P-value |
|---|---|---|---|---|
| Females (%) | 40 (35) | 93 (35) | 31 (40) | 0.7 |
| Recipient age (years): mean (range) | 31.7 (11.8–56.6) | 38.0 (15.0–74.8) | 42.1 (11.9–62.8) | <0.0001 |
| Donor age (years): mean (range) | 31.5 (15.5–54.8) | 37.0 (15.7–68.9) | 41.4 (18.8–59.6) | <0.0001 |
| Recipient race | 0.003 | |||
| Caucasian | 113 (99) | 256 (98) | 68 (88) | |
| Black | 0 | 1 (0.4) | 2 (2.5) | |
| Donor race (%) | 0.02 | |||
| Caucasian | 112 (98) | 255 (97) | 68 (88) | |
| Black | 0 | 2 (0.8) | 2 (2.5) | |
| Primary transplants | 108 (95) | 235 (90) | 69 (90) | 0.4 |
| ESRD etiology (%) | <0.0001 | |||
| Diabetes | 52 (46) | 108 (41) | 21 (27) | |
| FSGS | 1 (0.9) | 9 (3) | 4 (5) | |
| Glomerulonephritis | 32 (28) | 65 (25) | 20 (26) | |
| Anatomic/obstructive | 14 (12) | 38 (15) | 18 (23) | |
| Peak PRA (%) | 0.6 | |||
| 0% | 79 (69) | 199 (76) | 59 (77) | |
| 1–50% | 23 (20) | 42 (16) | 14 (18) | |
| 51–100% | 12 (11) | 21 (8) | 4 (5) | |