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. 2013 Oct 1;7(10):24–33. doi: 10.3941/jrcr.v7i10.1593

Table 1.

Summary table of thyroid carcinoma arising in struma ovarii

Etiology Unknown
Incidence Struma ovarii: 5% of all ovarian teratomas
Thyroid-carcinoma arising in struma ovarii: 5–10%
Papillary carcinoma - 70% (classical subtype - 44%; follicular variant subtype -26%)
Follicular carcinoma - 30%
Gender ratio Women
Age predilection 4th–6th decade
Risk factors Lesions> 16cm; Strumosis
Treatment Unilateral or bilateral salpingo-oophorectomy (depending on age) + total thyroidectomy
Prognosis Still unknown
Findings on imaging
  • US - Mixed solid and cystic mass, exhibiting abundant and low resistance flow within the central solid component on color Doppler imaging

  • CT - Multiloculated cystic mass presenting fluid with variable density between locules; Calcifications may be identified

  • MR - Multiloculated cystic mass presenting fluid with variable signal intensity (“stained glass appearance”) among locules and a solid component, which usually displays avid gadolinium enhancement. The fatty component is not a common feature, except when it occurs in association with mature cystic teratoma. Ascites can be present.

  • NOTE: The diagnosis of malignant thyroid tissue is based on microscopic findings.