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. 2014 Jan 6;10:25–32. doi: 10.2147/VHRM.S54159

Table 1.

Potential mechanisms for NSAID-associated increase in stroke risk

Vasoconstriction secondary to inhibition of prostacyclin-induced vasodilation
Hypertension induced by direct renal effects on sodium excretion leading to volume expansion
Thrombosis due to prostaglandin-mediated platelet aggregation

Abbreviation: NSAID, nonsteroidal anti-inflammatory drug.