Table 3. Frequency of CYP3A5 alleles and haplotypes, and CYP3A5 phenotypes in Brazilians.

CYP3A5	Overall cohort (909)	Self-identified Color groups
		White (308)	Brown (296)	Black (305)	P valuea
Alleles
*1	0.21	0.15	0.26	0.32	<0.0001
*3	0.73	0.82	0.68	0.52
*6	0.04	0.02	0.05	0.11
*7	0.03	0.01	0.04	0.08
Haplotypes
*1/*1	0.04	0.01	0.06	0.12	<0.0001
*1/*3	0.29	0.27	0.32	0.28
*1/*6	0.03	0.01	0.04	0.06
*1/*7	0.02	0.01	0.03	0.06
*3/*3	0.55	0.67	0.47	0.27
*3/*6	0.03	0.02	0.05	0.10
*3/*7	0.04	0.01	0.06	0.12
*6/*6	0.01	0	0.01	0.02
*6/*7	0	0	0	0.02
Phenotypes
Full-activity	0.04	0.01	0.06	0.12	<0.0001
Reduced-activity	0.34	0.29	0.39	0.41
Null-activity	0.62	0.7	0.55	0.47

^aComparison across the three Color groups (chi square or Fisher exact tests).