Table 6. Comparison of K+ channel subunit expression levels between myopathic and normal RV's.
Subunit | Normal | Myopathic | P-Value |
Kv1.4 | 8.43±0.87 | 20.35±2.32 | <0.001 |
Kv1.7 | 5.77±1.25 | 0.69±0.33 | 0.002 |
Kv3.3 | 2.18±0.24 | 1.52±0.16 | 0.038 |
Kv4.3 | 26.07±1.73 | 18.17±1.62 | 0.005 |
Kv11.1/HERG | 195.47±14.86 | 115.55±3.47 | <0.001 |
KvLQT1 | 91.47±3.23 | 63.01±3.23 | 0.001 |
TWIK-1 | 80.93±8.82 | 52.64±7.18 | 0.026 |
Kir2.1 | 95.99±12.98 | 169.16±29.44 | 0.004 |
Kir2.2 | 90.23±9.83 | 53.12±2.47 | 0.039 |
Kir2.3 | 46.48±6.30 | 84.15±8.27 | 0.003 |
Kir3.4 | 20.90±13.92 | 12.32±2.22 | 0.036 |
Kir6.2 | 41.44±6.10 | 27.26±2.26 | 0.047 |
Kvβ1 | 10.66±1.04 | 16.91±1.50 | 0.004 |
KCHIP2 | 320.57±22.74 | 119.68±25.22 | <0.001 |
TASK2 | 2.27±0.47 | 0.97±0.18 | 0.021 |
MinK | 11.80±0.99 | 16.82±1.83 | 0.003 |
SUR1 | 3.84±0.84 | 8.26±1.57 | 0.026 |
Units for all values are 2−ΔCt versus reference gene (×100), expressed as mean ± SEM. Only expression comparisons achieving p<0.05 are presented.