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. 2014 Jan 10;9(1):e78995. doi: 10.1371/journal.pone.0078995

Table 1. Clinicopathologic characteristics of the patients.

Characteristics Patients (n = 111)
No (%) No. of Relapse (%) No. of No Relapse (%)
Event 111(100) 33 (29.7)
Group by Integration pattern
Group 1a 31 5 26
Group 2b 24 5 19
Group 3c 37 12 25
Group 4d 14 7 7
HPV type
16 87 23 (26.4) 64 (73.6)
18 16 8 (50) 8 (50)
58 8 2 (25) 6 (75)
Stage group
∼IIB 86 19 (22.1) 67 (77.9)
III/IVA 18 9 (50.0) 9 (50.0)
IVB 7 5 (71.4) 2 (28.6)
Nodal status *
Negative 44 7 (15.9) 37 (84.1)
Positive 67 26 (38.8) 41 (61.2)
Histologic Grade
well/moderate 91 24 (26.4) 67 (73.6)
Poor 19 9 (47.4) 10 (52.6)
Histologic type
SCC 100 (90) 27 (27) 73 (73)
AD 9 (10) 4 (44.4) 5 (55.6)
ASC 2 2 (100) 0 (0)
Smoking
Never 94 (84) 26 (27.7) 68 (72.3)
Ever 17 (16) 7 (42.2) 10 (58.8)
Age median, 58; range, 27–81

a Group 1, Single copy HPV integration with episomal components;

b Group 2, Single copy HPV integration without episomal components;

c Group 3, Multicopy tandem repeated integration;

d Group 4, low HPV.

Abbreviations: AD/ASC, adenocarcinoma/adenosquamous carcinoma; SCC, squamous cell carcinoma.

Pelvic lymph nodes only 66, Pelvis+para-aortic lymph nodes 31.