Table 1. Clinicopathologic characteristics of the patients.
Characteristics | Patients (n = 111) | ||
No (%) | No. of Relapse (%) | No. of No Relapse (%) | |
Event | 111(100) | 33 (29.7) | |
Group by Integration pattern | |||
Group 1a | 31 | 5 | 26 |
Group 2b | 24 | 5 | 19 |
Group 3c | 37 | 12 | 25 |
Group 4d | 14 | 7 | 7 |
HPV type | |||
16 | 87 | 23 (26.4) | 64 (73.6) |
18 | 16 | 8 (50) | 8 (50) |
58 | 8 | 2 (25) | 6 (75) |
Stage group | |||
∼IIB | 86 | 19 (22.1) | 67 (77.9) |
III/IVA | 18 | 9 (50.0) | 9 (50.0) |
IVB | 7 | 5 (71.4) | 2 (28.6) |
Nodal status * | |||
Negative | 44 | 7 (15.9) | 37 (84.1) |
Positive | 67 | 26 (38.8) | 41 (61.2) |
Histologic Grade | |||
well/moderate | 91 | 24 (26.4) | 67 (73.6) |
Poor | 19 | 9 (47.4) | 10 (52.6) |
Histologic type | |||
SCC | 100 (90) | 27 (27) | 73 (73) |
AD | 9 (10) | 4 (44.4) | 5 (55.6) |
ASC | 2 | 2 (100) | 0 (0) |
Smoking | |||
Never | 94 (84) | 26 (27.7) | 68 (72.3) |
Ever | 17 (16) | 7 (42.2) | 10 (58.8) |
Age | median, 58; | range, 27–81 |
a Group 1, Single copy HPV integration with episomal components;
b Group 2, Single copy HPV integration without episomal components;
c Group 3, Multicopy tandem repeated integration;
d Group 4, low HPV.
Abbreviations: AD/ASC, adenocarcinoma/adenosquamous carcinoma; SCC, squamous cell carcinoma.
Pelvic lymph nodes only 66, Pelvis+para-aortic lymph nodes 31.