Table 2.

Individual ALS Patient Demographic Information

	Sex	Age (y)	Hand	H.S.D. (kg)	Onset location	ALSFRS-r	DD (mo)
1	M	65.1	R	0.61	UEs	29	12.07
2	F	56.5	R	2.28	Left LE	33	26.07
3	M	60.6	R	14.39	Left LE	44	26.97
4	M	58.1	R	11.52	Bulbar	40	16.67
5	F	68.5	R	3.63	Bulbar	37	14.00
6	F	61.4	R	10.61	UE & LE	42	9.46
7	M	55.5	R	9.09	Right UE	43	14.73
8	F	67.8	R	0.76	Bulbar	43	10.17
9	F	65.8	R	7.42	Left LE	33	15.90
10	M	66.8	R	3.03	LEs	40	7.77
11	M	51.9	R	12.88	Left UE	31	11.80
12	M	64.8	R	N/Aa	Right LE	45	12.07
13	M	56.7	R	0.75	Bulbar	39	13.17
14	M	58.3	R	10.61	Right UE	46	20.77
15	F	45.9	Rb	4.85	Left UE	33	13.63
16	M	63.8	Lc	0	UEs	33	21.03
17	M	63.3	R	5.75	LEs	38	61.70
18	F	65.9	R	4.40	Bulbar	26	56.17
19	M	47.1	R	6.51	UEs	36	56.20
20	F	55.3	R	25.00	Left UE	46	1.73
21	M	56.1	R	13.78	Left UE	38	7.80

^aHand strength could not be obtained for Subject 12 at the time of scanning.

^bSubject 15 reported left-handedness before disease onset, but due to weakness used the right hand at the time of the scan. This patient was considered left-handed according to the Edinburgh Inventory (13).

^cSubject 16 reported right-handedness before disease onset, but due to weakness used the left hand at the time of the scan. This patient was considered right-handed according to the Edinburgh Inventory (13).

H.S.D. = hand strength disparity; ALSFRS-r = ALS functional rating scale, revised version (total possible score is 48); DD = disease duration, defined as months between symptom onset and testing date; UE = upper extremity; LE = lower extremity.