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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: J Int Assoc Provid AIDS Care. 2013 May 24;13(5):402–408. doi: 10.1177/2325957413488185

Table 3.

Multivariate regression analysis of risk factors for mortality and immunologic response, stratified by education level and gender

Variable Overall (N=466)
High level of education a (N=188)
Low level of education b (N=278)
Males (N=156)
Females (N=310)
HR (95% CI) c P Value HR (95% CI) c P Value HR (95% CI) c P Value HR (95% CI) c P Value HR (95% CI) c P Value
Mortality
High level of education (Ref: low level of education) 1.76 (0.84–3.70) 0.13 NA NA NA NA 1.26 (0.25 – 6.39) 0.78 1.57 (0.65 – 3.77) 0.32
Males (Ref: females) 1.53 (0.73 – 3.22) 0.26 1.69 (0.55 – 5.21) 0.36 1.61 (0.56 – 4.67) 0.38 NA NA NA NA
Baseline CD4+ count (by 50 cells/mm3 decrease) 1.34 (0.98 – 1.83) 0.06 1.85 (1.07 – 3.17) 0.03 1.01 (0.67 – 1.52) 0.96 1.37 (0.76 – 2.48) 0.30 1.32 (0.91 – 1.93) 0.15
Baseline WHO stage 4 HIV infection 2.72 (1.28 – 5.74) 0.01 3.06 (1.19 – 7.92) 0.02 2.57 (0.68 – 9.80) 0.17 8.77 (1.87 – 41.06) 0.01 1.96 (0.74 – 5.18) 0.17
Sustained Immunologic Response d
High level of education (Ref: low level of education) 1.03 (0.78 – 1.37) 0.82 NA NA NA NA 1.16 (0.64 – 2.11) 0.62 0.99 (0.72 – 1.38) 0.97
Males (Ref: females) 0.66 (0.48 – 0.91) 0.01 0.74 (0.44 – 1.26) 0.27 0.63 (0.42 – 0.94) 0.02 NA NA NA NA
Baseline CD4+ count (by 50 cells/mm3 decrease) 0.90 (0.82 – 1.00) 0.05 0.87 (0.72 – 1.05) 0.14 0.92 (0.81 – 1.04) 0.16 0.87 (0.74 – 1.02) 0.09 0.92 (0.81 – 1.04) 0.19
Baseline WHO stage 4 HIV infection 1.18 (0.78 – 1.79) 0.42 1.07 (0.58 – 1.95) 0.83 1.42 (0.80 – 2.52) 0.23 1.10 (0.42 – 2.88) 0.84 1.20 (0.75 – 1.91) 0.44

Abbreviations: HR (Hazard Ratio); Ref (Reference); WHO (World Health Organization); NA (Not Applicable)

a

High level of education refers to those individuals who have completed secondary school or attended college or university.

b

Low level of education refers to those individuals who have primary school or less or some secondary school.

c

Multivariate model adjusted for the following factors (in addition to variables listed in table): age, occupation, number of children, past history of TB, Karnofsky score, baseline viral load

d

Immunologic response was defined as a sustained CD4+ ≥ 200 cells/mm3 from 6 months post-ARV initiation.