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. 2013 Oct 29;122(1):34–42. doi: 10.1289/ehp.1307280

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Effect of inhaled LPS dose on airway response to subsequent allergen challenge. Airway resistance (R; cmH₂0/mL/sec) was measured in anesthetized C57BL/6J mice that were sensitized to OVA using LPS, challenged with aerosolized OVA on a single occasion or on 6 consecutive days, and administered aerosolized methacholine (0–50 mg/mL). Values shown are peak R values (mean ± SE) and represent one of two experiments yielding similar results (n = 6 mice/group). *p < 0.05 compared with 0 μg LPS (OVA-only controls). **p < 0.05 for lower LPS dose compared with 10^–1 μg LPS.