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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Ann Biomed Eng. 2013 Jul 11;42(2):415–431. doi: 10.1007/s10439-013-0855-x

Table 2.

Elastic modulus and ultimate stress of human fibroatheroma.

Reference Elastic Modulus (kPa) Ultimate stress (kPa) Tissue Method
Lendon et al., 1988 (47) --- --- 12-1,938 C, Cap Thoracic aorta, Isolated cap Uniaxial tensile test

Lendon et al., 1991 (49) --- --- ~590±100 C, Healthy Aorta, Isolated cap Uniaxial tensile test
--- --- ~200±50 C, Cap

Lee et al., 1991 (45) 510±220 R, Ce --- --- Abdominal aorta, Isolated cap Cyclic compression test @ 1Hz, LEM
900±220 R, HCe --- ---
2,190±990 R, Cal --- ---

Lee et al., 1992 (46) 41±19 NF --- --- Abdominal aorta, Isolated cap Unconfined compression creep test, LEM
82±33 F --- ---
355±245 Cal --- ---

Lendon et al., 1993 (50) --- --- 100 and 500 --- Aorta ---

Cheng et al., 1993 (13) --- --- 545±160 C, Hist, Ruptured Coronary 2D FEA, LEM

Loree et al., 1994 (51) 927±468 C, Ce 484±216 C, Cap Abdominal / Thoracic aorta, Isolated cap Quasi-static creep tensile test, QSF Tangential modulus
2,312±2,180 C, HCe
1,466±1,284 C, Cal

Huang et al., 2001 (34) --- --- 286 C, Hist, Stable Coronary 2D FEA, SEDF using Mooney-Rivlin mat.
--- --- 458 C, Hist, Ruptured

Holzapfel et al., 2004 (31) 12,600±4,700 In, Cal 179±56 In, Cal Iliac One cyclic quasi-static uniaxial tensile test, followed by single tensile test to failure
--- --- 489±186 C, In, NAth
--- --- 944±272 L, In, NAth
--- --- 255±80 C, In, Cap
--- --- 469±100 L, In, Cap
--- --- 777±336 C, In, F
--- --- 278±98 L, In, F

Holzapfel et al., 2005 (30) 8 ± 5 C, Ad, μ 1,430±604 C, Ad, NAth Coronary Non atherosclerotic Uniaxial tensile test SEDF using Mooney-Rivlin material
39 ± 33 L, Ad, k1 1,300±692 L, Ad, NAth
1 ± 1 C, Me, μ 446±194 C, Me, NAth
22 ± 7 L, Me, k1 419±188 L, Me, NAth
28 ± 11 C, In, μ 394±223 C, In, NAth
264 ± 491 L, In, k1 391±144 L, In, NAth

Ebestein et al., 2009 (23) 230 ± 210 Thrombus --- --- Carotid Indentation test
270 ± 150 F --- ---
2,100 ± 5,400 Par Calc F --- ---
(690 ± 2300)×103 Calc --- ---

Barret et al., 2009 (3) 33 (21-300) F --- --- Carotid Indentation test

Teng et al., 2009 (81) --- --- 1,996±867 L, Ad Carotid Uniaxial tension test SEDF using first Piola-Kirchoff stress
--- --- 519±270 L, Me
--- --- 1,047±536 L, W
--- --- 1,802±703 C, Ad
--- --- 1,230±533 C, Me
--- --- 1,022±427 C, W

Maher et al., 2009 (54) 23±34 C10 --- --- Carotid Uniaxial tensile test SEDF using Mooney-Rivlin material
65±106 C01 --- ---
817±2,441 C20 --- ---
206±461 C11 --- ---
324±818 C02 --- ---

Claes et al., 2010 (16) --- --- 390±70 C, W, NAth Coronary, Non atherosclerotic Uniaxial tensile test

Sommer et al., 2010 (72) 28±14 L, Whole --- --- Carotid Non atherosclerotic Extension-Inflation test @ 1.1 stretch
77±23 L, Ad --- ---
97±10 L, Me-In --- ---
55±9 C, Whole --- ---
140±24 C, Ad --- ---
129±21 C, Me-In --- ---

Lawlor et al., 2011 (43) --- --- 366±220 C, W Carotid Uniaxial tensile test

Kural et al., 2012 (40) 8±3 L, LM --- --- Coronary Biaxial tensile test Low and high modulus from 2 linear regions of stress-strain curves. Coronary: LM (15±5), HM (175±25); Carotid LM (7.5±2.5), HM (45±5) kPa
17±19 C, LM --- --- Coronary
97±31 L, HM --- --- Coronary
90±39 C, HM --- --- Coronary
1±0 L, LM --- --- Carotid
1±0 C, LM --- --- Carotid
5±0 L, HM --- --- Carotid
6±1 C, HM --- --- Carotid

Abbreviations: Cellular (Ce), hypocellular (HCe), calcified (Cal), Fibrous (F), Non-Fibrous (NF), Longitudinal (L), Circumferential (C), Radial (R), Non-atherosclerotic (NAth), Histology cross section (Hist), Linear elastic model (LEM), Cubic strain function (QSF), Finite element analysis (FEA), Strain energy density function (SEDF),

Cij, i+j=1,2 material constants of hyperelastic model. Fraction numbers were rounding to its nearest whole integer value.