Table 3.
Cytotoxicity of hydromethanolic extract of Sapindus saponaria aerial parts and ellipticine (standard) in human tumor cell lines and in nontumor liver primary culture.
| Extract (GI50, μg/mL) | Ellipticine (GI50, μg/mL) | |
|---|---|---|
| HCT-15 (colon carcinoma) | 362.76 ± 14.64 | 1.91 ± 0.06 |
| HepG2 (hepatocellular carcinoma) | >800 | 3.22 ± 0.67 |
| HeLa (cervical carcinoma) | 258.58 ± 3.40 | 1.14 ± 0.21 |
| MCF-7 (breast carcinoma) | 376.34 ± 19.66 | 0.91 ± 0.04 |
| NCI-H460 (lung carcinoma) | 368.29 ± 18.94 | 1.42 ± 0.00 |
|
| ||
| PLP2 (nontumor liver cells) | >800 | 2.06 ± 0.03 |
GI50 values correspond to the sample concentration achieving 50% of growth inhibition in human tumor cell lines or in liver primary culture PLP2.