Table 5.

RR of all-cause mortality (excluding suicide) and cardiac mortality in exposed cohort, psychiatric nonuser cohort, and general population controls.

Outcome	Exposure	No. of cases	Incidence rate per 1000 person-years	Age, sex-adjusted relative risk (RR) (95% CI)	Fully adjusted RR (aRR) (95% CI)
All-cause mortality	General population	41,546	39.6	Reference	Reference
	Current use	23,841	86.1	2.98 (2.93–3.03)‡	2.72 (2.67–2.77)‡
	Psychiatric nonusers	7,765	25.3	Reference	Reference
	Current use	23,841	86.1	2.15 (2.10–2.21)‡	1.75 (1.64–1.87)‡
Cardiac mortality	General population	6,532	11.9	Reference	Reference
	Current use	2,478	17.0	2.01 (1.92–2.10)‡	1.83 (1.74–1.93)‡
	Psychiatric nonusers	1,289	6.4	Reference	Reference
	Current use	2,478	17.0	1.62 (1.52–1.74)‡	1.72 (1.42–2.07)‡
SCD-primary definition	General population	46	0.8	Reference	Reference
	Current use	44	2.7	4.45 (2.94–6.73)‡	4.03 (2.63–6.16)‡
	Psychiatric nonusers	10	0.4	Reference	Reference
	Current use	44	2.7	5.76 (2.90–11.45)‡	5.76 (2.90–11.45)‡
SCD-secondary definition	General population	244	4.0	Reference	Reference
	Current use	178	11.0	3.48 (2.87–4.23)‡	2.89 (2.32–3.60)‡
	Psychiatric nonusers	98	4.1	Reference	Reference
	Current use	178	11.0	2.36 (1.84–3.02)‡	2.15 (1.64–2.81)‡
SCD-tertiary definition	General population	370	2.3	Reference	Reference
	Current use	198	4.6	2.47 (2.08–2.94)‡	2.11 (1.73–2.56)‡
	Psychiatric nonusers	119	1.8	Reference	Reference
	Current use	198	4.6	1.92 (1.53–2.42)‡	1.79 (1.42–2.27)‡
CHD	General population	5,993	6.6	Reference	Reference
	Current use	1,269	5.4	1.06 (1.00–1.13)*	0.94 (0.87–1.00)*
	Psychiatric nonusers	982	3.5	Reference	Reference
	Current use	1,355	5.7	1.08 (1.00–1.18)*	1.16 (0.94–1.44)
Ventricular arrhythmias	General population	1,977	2.2	Reference	Reference
	Current use	646	2.7	1.53 (1.40–1.67)‡	1.49 (1.35–1.64)‡
	Psychiatric nonusers	500	1.8	Reference	Reference
	Current use	646	2.7	1.14 (1.01–1.28)†	1.16 (1.02–1.31)†

*P < 0.10, ^† P < 0.05, ^‡ P < 0.01.