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. 2013 Dec 26;2013:848043. doi: 10.1155/2013/848043

Table 4.

SEDDSs and their potential to solve various problems associated with the drug molecule.

BCS class Problems proposed to be solved by SEDDS
BCS class I Enzymatic degradation, acidic degradation, gastric irritation, gut wall efflux
BCS class II Solubilization, pH dependent solubilization, low bioavailability
BCS class III Enzymatic degradation, gut wall efflux, low permeability, low bioavailability
BCS class IV Solubilization, enzymatic degradation, gut wall efflux, low permeability, low bioavailability