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. Author manuscript; available in PMC: 2014 Jan 12.
Published in final edited form as: Pediatr Res. 2012 Jul 20;72(4):375–383. doi: 10.1038/pr.2012.96

Figure 3.

Figure 3

Histomorphological profile. (a) Expansion index, total lung. (b) Expansion index, regional lung. (c) Number of opened gas exchange units per fixed field, total lung. (d) Number of opened gas exchange units per fixed field, regional lung. For (b) and (d), open bars are nondependent, solid bars are dependent lung. Independent of lung region, the expansion index of lungs from lambs treated with SRT was greater (*P < 0.01) than those not treated with surfactant. Regional differences in expansion were noted for beractant-treated lungs, with less (**P < 0.001) expansion in the dependent than the nondependent region and as compared with the dependent region of lungs treated with lucinactant. The number of expanded gas exchange units was greater (*P < 0.01) in lucinactant- or poractant alfa–treated lungs than those not treated with surfactant, independent of region. Relative to beractant-treated lungs, the number of expanded gas exchange units was greater (**P < 0.001) in those treated with lucinactant. SRT, surfactant replacement therapy.