Table 1.
Clinical features of patients with PPCD and steep corneal curvature (> 48.0 D OU)
| Patient | Sex | Eye | Simulated Keratometry | Keratoconus | ZEB1 Mutation | |||
|---|---|---|---|---|---|---|---|---|
| Steep K | Flat K | Average K | Clinical Features | Topographic Features | ||||
| 1 | M | OD | 50.50 | 49.50 | 50.00 | No | No | p.(Gln12*) |
| OS | 50.75 | 48.25 | 49.50 | No | No | |||
| 2* | M | OD | 52.08 | 48.70 | 50.39 | No | Yes (Inferonasal steepening) | p.(Gln884fs) |
| OS | 49.34 | 47.87 | 48.61 | No | Yes (Inferonasal steepening) | |||
| 3 | M | OD | 51.50 | 54.00 | 52.75 | No | No | No |
| OS | 51.25 | 52.25 | 51.75 | No | No | |||
| 4 | M | OD | 51.25 | 55.75 | 53.50 | No | No | p.(Gln214*) |
| OS | 55.25 | 55.72 | 55.49 | No | No | |||
| 5 | M | OD | 55.00 | 56.00 | 55.50 | No | No | No |
| OS | 53.50 | 53.50 | 53.50 | No | No | |||
| 6 | F | OD | 57.00 | 57.00 | 57.00 | No | No | p.(Glu495fs) |
| OS | 55.50 | 58.00 | 56.75 | No | No | |||
| 7** | F | OD | 56.20 | 57.98 | 57.09 | No | No | p.(Arg325*) |
| OS | 58.02 | 59.32 | 58.67 | No | No | |||
| 8** | F | OD | 58.46 | 61.26 | 59.86 | No | No | p.(Arg325*) |
| OS | 56.02 | 59.21 | 57.62 | No | No | |||
| 9 | F | OD | 58.60 | 56.80 | 57.70 | Yes (conical corneal deformation; central and interior corneal thining; s/p hydrops) | Yes (Central corneal steepening; anterior protrusion of posterior corneal profile) | No |
| OS | 55.40 | 53.50 | 54.45 | Yes (conical corneal deformation; central and interior corneal thining; s/p hydrops) | Yes (Central corneal steepening; anterior protrusion of posterior corneal profile) | |||
| 10 | F | OD | 59.31 | 56.72 | 58.02 | Yes (conical corneal deformation) | Yes (Central corneal steepening) | No |
| OS | 64.90 | 59.52 | 62.21 | Yes (conical corneal deformation) | Yes (Central corneal steepening) | |||