Fig. 4.

Dynamics of spontaneous CA activation. Right: Time-courses of area-specific average CA activations for the six different cortical areas modelled. Left insets: dynamics of the first few time steps of spontaneous CA ignition. Note the earlier (time-step 1) rise of CA activity in the two central areas (PA, PF: purple and cyan curves), followed by secondary (HP, PM: step 2) and primary (P1, M1: step 3) areas. Top: CA activation quantified as total number of active CA cells per area. Central areas exhibit larger numbers of active CA cells than secondary and primary ones due to CA distribution. Bottom: normalised CA activation data (to remove the confounding effects of CA size, top graphs values are divided by area-specific CA size). While the maximal CA activation levels are now comparable (right), the two central areas still exhibit earlier activation than secondary and primary areas (left).