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. 2014 Jan 13;7:285. doi: 10.3389/fncel.2013.00285

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Copyright © 2014 Pai, Siripornmongcolchai, Berentsen, Pakzad, Vieuille, Pallesen, Pajak, Simpson, Armstrong, Wibrand and Bramham.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Axon navigation pathway targeting by miRNAs that differentially associate with Ago2 in an activity-dependent manner. Genes targeted by miRNAs that differentially associate with Ago2 in an activity-dependent manner are color coded by whether they are targeted by enhanced (green box), depleted (red box), or by both enhanced and depleted miRNAs (brown box). The involvement of all four guidance molecule families and their convergence on signal transduction systems classically associated with activity-dependent synaptic plasticity suggests an important role for these receptor mediated signaling pathways in plasticity.