Table 6.

Comparison between the PD subgroup with worsening of speech performance with the PD subgroup with unchanged or amelioration of speech performance under stimulation.

	PD group with worse speech performance under stimulation/(n = 8, 6 male)			PD group with unchanged or better speech performance under stimulation/(n = 30, 16 male)	Comparison of patients with speech worsening with the group with unchanged/better speech performance, both in the OFF condition
	StimOFF condition Median/1.–3. quartile	StimON condition Median/1.–3. quartile	Comparison OFF vs. ON	StimOFF condition Median/1.–3. quartile
UPDRS III	48/40.25–52.75	23.5/13.25–33	p < 0.001	47/31.5–46.25	p = 0.024
UPDRS speech item	1/1–2	1.5/1–2	n.s.	1/1–2	n.s. (p = 0.102)
Perceptual analysis/sum score	6/4.5–7.75	7/7–8.75	p = 0.001	5/3–7	n.s. (p = 0.122)
Voice	1.5/1–2	1.5/1–2	n.s.	1/1–2	n.s.
Articulation	2/1–2	2/2–2	p = 0.033	2/1–2	n.s.
Fluency	2/1–2.75	2.5/1.25–3	n.s. (p = 0.08)	1/1–2	n.s. (p = 0.065)
Prosody	1/1–2	1.5/1–2	n.s. (p = 0.08)	1/0–1	n.s.
Acoustic analysis	Mean/SD	Mean/SD		Mean/SD
Jitter	1.535/1.244	1.560/1.304	n.s.	2.211/2.087	n.s.
Shimmer	8.551/6.256	9.062/7.097	n.s.	11.335/7.483	n.s.
nhR	0.064/0.063	0.061/0.068	n.s.	0.092/0.105	n.s.
Loudness (dB)	71.17/6.70	72.15/4.73	n.s.	69.72/7.83	n.s.
MeanF0 male	124.13/16.90	123.44/15.17	n.s.	117.75/20.09	n.s.
MeanF0 female	168.34/8.05	192.50/0.30	(n.a.)	169.41/45.69	(n.a.)
VAI male	0.681/0.075	0.648/0.065	n.s.	0.648/0.070	n.s.
VAI female	0.704/0.057	0.674/0.154	(n.a.)	0.723/0.063	(n.a.)
Pinw%	8.14/7.72	7.09/7.86	n.s.	17.50/10.56	p = 0.025
NSR	5.46/1.48	5.48/1.61	n.s.	5.26/0.99	n.s.
PR%	19.30/10.07	21.26/7.19	n.s.	16.75/8.87	n.s.
AA	0.95/0.73	0.61/0.63	n.s.	0.19/0.40	p = 0.022
F0SD male	15.94/2.80	14.24/3.93	n.s.	14.30/4.18	n.s.
F0SD female	16.16/1.58	19.60/5.99	(n.a.)	16.85/5.68	(n.a.)

(n.a.): statistical analysis not applicable because of small sample size.