Table 2.
Multivariate associations of breast cancer risk factors with subsequent risk of breast cancer among women biopsied for benign breast disease.
| Cases (N=661) | Controls (N=696) | Multivariate odds ratio* | 95% CI | |
|---|---|---|---|---|
| Age at first live birth/number of pregnancies | ||||
| Nulliparous | 132 | 99 | 1.00 | Reference |
| ≥25 yrs/ <3 | 145 | 121 | 0.81 | 0.51-1.28 |
| ≥25 yrs/ ≥3 | 50 | 74 | 0.44 | 0.25-0.78 |
| <25 yrs/ <3 | 113 | 154 | 0.53 | 0.33-0.86 |
| <25 yrs/ ≥3 | 149 | 184 | 0.49 | 0.13-0.79 |
| Missing | 72 | 64 | ||
| Family history of breast cancer | ||||
| No | 528 | 583 | 1.00 | Reference |
| Yes | 107 | 93 | 1.24 | 0.85-1.80 |
| Missing | 26 | 20 | ||
| Menopausal status | ||||
| Premenopausal | 364 | 352 | 1.00 | Reference |
| Perimenopausal | 63 | 82 | 0.76 | 0.44-1.32 |
| Postmenopausal | 234 | 262 | 0.60 | 0.37-0.99 |
Adjusted for the other variables in the table, as well as histology (no BBD/non-proliferative disease, proliferative disease without atypia, atypical hyperplasia).