Metabolite composition of fluoranthene generated from colon tumor microsomal metabolism of fluoranthene. The ApcMin mice were preexposed to benzo(a)pyrene and microsomes were isolated and incubated with fluoranthene alone or in combination with benzo(a)pyrene. Values are expressed as the percentage of individual metabolite types among the total metabolites (sum of individual concentrations of FLA 2, 3-diol, trans-2, 3-dihydroxy-1, 10b-epoxy-1, 2, 3, 10b tetrahydro FLA [2, 3D FLA]; 3-hydroxy FLA; and 8-hydroxy FLA) formed (n=5 for each treatment category). See the legend for Fig. 3 for explanation of abbreviations