Table 3.
Reference | Years | Average Age of “AD” or affected population | Genes linked to hippocampal atrophy in MRI-based GWAS |
---|---|---|---|
[89] | 2009 | 75 | S100A5, SCAMP1-LHFPL2, ARSB, EFNA5, IKZF1-AC020743.7, MAGI2, MAL2, PRUNE2, RP11, ETS1, ARID2-SFRS2IP, CNAD1, FRMD6, C20orf132, RPN2, ZBP1, FDPSP |
[102] | 2010 | 76 | EPHA4, APOE, TP63, NXPH1, UBE2D1 |
[104] | 2010 | 76 | ZNF326, UTP20 |
[26] | 2011 | 73 | TTR |
[34] | 2011 | 75 | ZNF292, PICALM |
[70] | 2012 | 75 | SLC1A7, LPHN2, F5/SELP, ATF3, GCFC2, STXBP5L, NKAIN2, VPS13B, TLE1, PICALM, LHFP, DLGAP1, APOE, COL18A1 |
[105] | 2012 | 75 | TESC, HMGA2, DDR2 |
[55, 56] | 2012 | 75 | MACROD2, SORCS2, GRIN2B, GALNTL4, NRXN3, AK130123,MAGI2, NPAS3, RBFOX1, AY229892, ZMAT4, STAGS3L2, GAS7, ADARB2, GABRG3, CDH4, CLSTN2, CDH13, GALNTL6, GALNTL6, PRKAG2, CHODL |
[13] | 2012 | Multiple cohorts | MSRB3-WIF1, HRK-FBXW8, DPP4, ASTN2 |
[68, 69] | 2013 | 76 | Complex patterns of genes with hypothesized interactions |
Highly overlapping sample attainment in these studies