. Author manuscript; available in PMC: 2014 Dec 28.

Published in final edited form as: J Control Release. 2013 Oct 2;172(3):1045–1064. doi: 10.1016/j.jconrel.2013.09.026

Table 2.

Summary of toxicities for various paclitaxel-based cancer treatments.

Drug	Taxol [104]		Abraxane [97]		NK105 [105]		Xyotax [106]		Genexol-PM [107]
Paclitaxel Dose	175 mg/m²		260 mg/m²		150 mg/m²		210 mg/m²		300 mg/m²
	All	Severe	All	Severe	All	Severe	All	Severe	All	Severe
Neutropenia	82	22	80	9	91	65	21	14	71	46
Anemia	-	-	33	1	54	12	17	5	19	3
Platlet	3	1	2	1	28	0	7	2	2	0
Nausea	22	1	30	3	28	0	33	4	70	3
Vomiting	10	1	18	4	-	-	19	2	52	3
Diarrhea	15	1	26	1	23	0	16	1	25	2
Fatigue	39	3	47	8	58	4	27	6	7	3
Arthralgia	49	4	44	8	46	2	12	<1	29	7
Myalgia	49	4	44	8	60	0	-	-	54	6
Neuropathy	56	2	71	10	65	2	50	19	71	13
Alopecia	94	N/A	90	N/A	88	N/A	9	N/A	81	N/A
AST	32	N/A	36	N/A	32	N/A	-	-	-	-
Hypersensitivity	12	2	4	0	-	-	-	-	7	4