Table 2. Clinical details of three categories of index patients: 10–50 adenomas, 50–100 adenomas and >100 adenomas.

Panel A
Index					Personal history
Adenomas (n)	Number		Mean age	Men (%)	CRC		Men (%)	Age at CRC	Duodenal adenoma
10–50	160	63%	53 (29–82)	63	59	37%	56	53 (26–75)	7/20	35%
50–100	53	21%	51 (13–73)	57	18	34%	72	55 (37–73)	1/17	6%
>100	39	15%	44 (4–80)	56	19	49%	58	51 (29–80)	7/44	16%
Total	252	100%	51 (4–82)	60	96	38%	59	53 (26–80)	15/81	19%
Panel B Family history
Adenomas (n)	FH			FDRs with CRC (n)		Age at CRC		FDRs with polyps (n)	Age
10–50	95		59%	72		61 (32–85)		68		55 (30–85)
50–100	30		57%	20		62 (44–91)		21		55 (26–78)
>100	18		46%	12		56 (17–79)		14		51 (15–70)
Total	143		57%	104		60 (17–91)		103		55 (15–85)

Panel A: Clinical details of the index patients. Number of patients, percentage and mean age at diagnosis; number and percentage of male patients; number, percentage, sex distribution and age at diagnosis of CRC in polyposis patients; number of patients with duodenal adenomas/patients who underwent upper gastrointestinal endoscopy.

Panel B: Clinical data of the first-degree relatives (FDRs) of the index patients. Number and percentage of index patients with a positive family history (FH), that is, FDRs with CRC and/or multiple adenomas (ie, <10 polyps).

CRC, colorectal cancer.