Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
OKN-007 inhibits TGFB1/SMAD2 and Hedgehog/GLI1 signaling in Huh7 cells. (A) OKN-007 treatment was shown to repress the TGFB1/SMAD2 signaling pathway in Huh7 cells by both SBE reporter luciferase activity assay and immunoblotting for phospho-SMAD2. (B) OKN-007 treatment was shown to suppress the Hh/GLI1 signaling pathway in Huh7 cells by both a GLI reporter luciferase activity assay and immunoblotting for GLI1 protein.
