Table 2.
Efficacy of different anthelmintics against H. bakeri as compared to Cry5B in vivo (Modified from Hu and Aroian 2012)
Anthelmintic | Dose given (μM/kg) | Dose relative to Cry5B | Day(s) treatment was given (PI = post infection) | % Reduction in intestinal worm burden | Publication references |
---|---|---|---|---|---|
Cry5B | 0.7 | 1x | 15 days PI | 70 | Hu et al. (2010a) |
Levamisole | 49 | 70x | 12 days PI | 90 | Fonseca-Salamanca et al. (2003) |
Ivermectin | 5.7 | 8x | 18 days PI | 87 | Githiori et al. (2003a) |
Pyrantel | 84 | 120x | 18 days PI | 99 | Githiori et al. (2003b) |
Mebendazole | 75 | 107x | 9–15 days PI | 84 | Wabo Pone et al. (2009) |
Tribendimidine | 2.2 | 3x | 15 days PI | 70 | Hu et al. (2010a) |