Mean (± SEM) A serotonin (5-HT) and B serotonin catabolite 5-HIAA concentrations in the commissural (Vc) nuclei of the ventral area of the subpallial region of the telencephalon. The Vc nuclei constitute putative amygdalar/striatal regions in the teleost. Trout injected icv with 2000 ng CRF (hatched bars) had significantly more 5-HT (* indicates significance; P < 0.05) than those given 500 ng CRF, artificial cerebrospinal fluid (aCSF, gray bars) or uninjected controls (clear bars). Dose of CRF injected icv (0 = uninjected + aCSF controls, 500 ng, or 2000 ng) is positively correlated with C 5-HT (linear regression: r2 = 0.38, P < 0.001) and D 5-HIAA (linear regression: r2 = 0.17, P < 0.029) in the subpallium. No correlations between E 5-HT (linear regression: r2 = 0.00, P > 0.95) or F 5-HIAA (linear regression: r2 = 0.08, P > 0.18) concentrations in subpallium and locomotion exist in rainbow trout.