Fig 1.

Delivery of AAV9.FI6 to airway confers partial protection against H7N9 A/H1. (A) Weights of mice following challenge with H7N9 A/H1. Open circles, control mice (n = 10); closed triangles, AAV9.FI6-treated mice (n = 14). (B) Survival of challenged mice. Mice were euthanized when they appeared in distress or their body weight declined ≥30%. Dashed lines, control mice; solid lines, AAV9.FI6-treated mice. (C) Timeline of the H7N9 A/H1 human infection report to animal vaccination and vector-mediated protection.