Table 1.

Evaluation and comparison of recombinant M. avium subsp. paratuberculosis proteins (MBP fusion and His-tagged proteins)

Protein type and function	Protein(s)
MBP fusion proteins
Phosphate metabolism	MAP0435c
Cold shock protein	MAP0810
Putative virulence factor	MAP1272c
Universal stress proteins	MAP1339
Cell wall synthesis	MAP2058c
Signal recognition	MAP3968
ATP and purine biosynthesis	MAP2450c, MAP3393c
Cell division	MAP0068, MAP1889c
Heat shock protein chaperone	MAP3268, MAP3701c
Response regulators	MAP0834c, MAP3200
Protein synthesis	MAP1027c, MAP4125
Proteolysis	MAP1834c, MAP2280c, MAP2281c
Amino acid metabolism	MAP1293, MAP1297, MAP1846c, MAP2864c
Antioxidant enzymes	MAP1588c, MAP1589c, MAP1653, MAP4340
Hypothetical protein	MAP0593c, MAP0184c, MAP1586, MAP3555, MAP3864
Fatty acid metabolism	MAP0508, MAP0516c, MAP1017c, MAP2698c, MAP2872c, MAP3190, MAP3577, MAP3651c
Cellular processes	MAP0187c, MAP0540, MAP1560, MAP1885c, MAP2411, MAP2487c, MAP2705c, MAP3007, MAP3538, MAP3567
His-tagged proteins
Putative virulence factor	MAP1272c
Fatty acid metabolism	MAP2698c
Cellular processes	MAP2487c, MAP3567