Table 3.

Antigenicity evaluation of MBP fusion proteins

Protein	Protein concn (μg/ml)	OD450 (n) for:		Pc	AUCROC
		Unexposed samples (23)	Exposed samples (23)
MAP0068a	5	0.133	0.218	0.002	0.71
MAP0184ca,b	10	0.215	0.355	0.002	0.745
MAP0187c	5	0.236	0.31	0.118
MAP0435c	20	0.278	0.291	0.797
MAP0508a,b	6	0.3	0.501	0.004	0.713
MAP0516ca,b	5	0.257	0.439	<0.001	0.758
MAP0540	7	0.298	0.36	0.238
MAP0810	10	0.187	0.241	0.111
MAP0834ca,b	5	0.141	0.216	0.002	0.742
MAP1027c	10	0.176	0.234	0.083
MAP1272ca,b	10	0.26	0.451	0.005	0.703
MAP1293a,b	5	0.186	0.292	0.012	0.717
MAP1297a,b	10	0.172	0.321	0.002	0.744
MAP1339	5	0.204	0.274	0.067
MAP1560	10	0.252	0.273	0.51
MAP1586	5	0.285	0.311	0.515
MAP1589c	10	0.183	0.269	0.02	0.677
MAP1653b	10	0.195	0.263	0.045	0.683
MAP1834ca,b	9	0.262	0.44	0.002	0.765
MAP1889c	5	0.215	0.203	0.652
MAP2058ca,b	6	0.265	0.442	0.005	0.703
MAP2281c	7	0.29	0.281	0.773
MAP2411	10	0.265	0.298	0.481
MAP2450ca,b	8	0.202	0.293	0.045	0.677
MAP2487c	8	0.307	0.331	0.576
MAP2705c	10	0.208	0.228	0.541
MAP2864ca,b	8	0.336	0.455	0.035	0.658
MAP2872ca,b	8	0.166	0.289	<0.001	0.765
MAP3007a,b	7	0.211	0.357	0.003	0.74
MAP3200b	10	0.216	0.339	0.008	0.699
MAP3268	10	0.272	0.229	0.386
MAP3393c	10	0.261	0.291	0.497
MAP3567a,b	1	0.137	0.234	0.002	0.728
MAP3577	7	0.194	0.215	0.465
MAP3651ca,b	5	0.208	0.323	0.01	0.695
MAP3701c	10	0.166	0.198	0.274
MAP3864b	10	0.208	0.289	0.048	0.642
MAP3968a,b	7	0.154	0.277	0.002	0.719
MAP4125	10	0.284	0.292	0.847
MAP4340b	10	0.194	0.296	0.006	0.732

^aProteins able to produce significantly higher OD values for serum samples obtained from sheep with paucibacillary infections than for serum samples from unexposed sheep.

^bProteins able to produce significantly higher OD values for serum samples that were low reactors in the Institut Pourquier ELISA than for serum samples from unexposed sheep.

^cMean OD values for the exposed group are significantly higher than those for the unexposed group (P < 0.05).