Table 4.

Antigenicity evaluation of MBP fusion and factor Xa-cleaved proteins

Protein	Protein concn (μg/ml)	Data for MBP fusion proteins				Data for factor Xa-cleaved proteins
		OD450 (n) for:		Pc	AUCROC	OD450 (n) for:		Pc	AUCROC
		Unexposed samples (23)	Exposed samples (23)			Unexposed samples (23)	Exposed samples (23)
MAP0593c	20	0.262	0.301	0.295		0.182	0.253	0.005	0.75
MAP1017c	10	0.203	0.266	0.046	0.687	0.206	0.314	0.005	0.753
MAP1588cb	10	0.167	0.243	0.027	0.702	0.153	0.206	0.033	0.662
MAP1846cb	10	0.158	0.239	0.022	0.702	0.178	0.23	0.029	0.708
MAP1885c	10	0.237	0.261	0.659		0.166	0.169	0.864
MAP2280cb	10	0.196	0.279	0.027	0.702	0.239	0.344	0.002	0.786
MAP2698c	4	0.207	0.268	0.15		0.197	0.239	0.007	0.7
MAP3190a,b	10	0.222	0.327	0.007	0.708	0.165	0.224	0.03	0.668
MAP3538b	10	0.172	0.247	0.022	0.703	0.188	0.264	0.001	0.792
MAP3555a,b	10	0.272	0.448	0.002	0.736	0.203	0.311	0.002	0.738

^aProteins able to produce significantly higher OD values for serum samples obtained from sheep with paucibacillary infections than for serum samples from unexposed sheep.

^bProteins able to produce significantly higher OD values for serum samples that were low reactors in the Institut Pourquier ELISA than for serum samples from unexposed sheep.

^cMean OD values for the exposed group are significantly higher than those for the unexposed group (P < 0.05).