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. 2013 Dec 13;16(1):172–180. doi: 10.1208/s12248-013-9554-7

Table I.

Spironolactone IC50 (micromolars) Values

Program Parameter Original %Control %Inhibition
WinNonlin® P app, BL-AP 9.277 3.280 1.371
ER 0.077 0.448 0.705
NSF 9.817 2.759 0.024
GraphPad® P app, BL-AP 3.279 3.308 3.308
ER 0.455 0.377 0.377
NSF 2.760 2.840 2.840
SigmaPlot® P app, BL-AP 3.280 3.280 3.280
ER 0.445 0.445 0.445
NSF 2.761 2.761 2.761