Fig. 3.

Chemistry–bioactivity fingerprint for licorice (10 μM). Chemistry fingerprint was obtained from licorice ethyl acetate (LEA) at 260 nm. Peaks 3–6 (intensity 65%, 100%, 78%, and 100%) were not fully displayed due to the limited space. Tested compounds and predicted compounds (inhibition percentage not shown) were marked with solid and hollow dots, respectively. 3A4 (M) and 3A4 (T) suggest activities evaluated by using midazolam and testosterone, respectively. Integrate chromatogram of LEA please refer to Fig. 6. The analytical method was described in ESM