Fig 5.

Conditioned media from CREB3L1-expressing cells induced less migration of endothelial cells. Data represent migration of the endothelial cell line EA.hy926 in wound-healing assays for 0, 6, 12, and 24 h (A and B) and chemotaxis assays for 8 h (C) in the presence of complete medium and conditioned media from LN4D6 and MDA-MB-435 cells transfected with vector only or CREB3L1 (×10 magnification). The results are representative of 3 independent experiments for the wound-healing assay data and the means ± SE of 3 independent experiments each with triplicate measurements for the chemotaxis data. **, P < 0.001.