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. 2013 Sep;20(9):1388–1395. doi: 10.1128/CVI.00270-13

Table 1.

Levels of total IgG and IgG subclasses before and after aP preschool booster vaccination

Time of assessment and antigen IgG and IgG subclass levels (EU/ml)a
Total IgG
 IgG1
 IgG2
 IgG3
 IgG4
wP aP wP aP wP aP wP aP wP aP
Prebooster (wP, n = 61; aP, n = 61)
    PT 4.5 7.7b 1.3 3.2b 1.7 1.7 0.02 0.05b 0.02 0.07b
    FHA 8.8 16b 6.2 14b 0.46 0.36 0.08 0.10 0.09 0.60b
    Prn 3.1 24b 1.8 20b 0.28 0.36 0.07 0.18b 0.02 0.67b
28 days postbooster (wP, n = 52; aP, n = 40)
    PT 61 187b 38 140b 5.5 4.6 0.65 0.56 0.40 14b
    FHA 195 521b 181 450b 2.0 8.2b 1.6 2.2 3.2 36b
    Prn 187 1253b 178 1215b 1.2 3.4b 1.3 1.2 1.3 18b
2 yr postbooster (wP, n = 63; aP, n = 61)
    PT 11c 26b,c 5.1c 16b,c 1.7 2.7 0.03 0.04 0.05c 0.38b,c
    FHA 45c 81b,c 42c 75b,c 0.16d 0.38b 0.10 0.08 0.97c 2.7b,c
    Prn 19c 110b,c 17c 103b,c 0.19 0.44b 0.11 0.14 0.27c 2.9b,c
a

Data are expressed as geometric mean values specific for PT, FHA, or Prn in children who were primed with either wP or aP. All values for 28 days postbooster were significantly increased (P < 0.05) compared with prebooster levels, and those for 2 years postbooster were significantly decreased (P > 0.05) compared with 28-day postbooster values.

b

Significantly increased levels in aP-primed children compared to wP-primed children (P < 0.05).

c

Significantly increased values in children 2 years after booster vaccination compared to prebooster levels (P < 0.05).

d

Significantly decreased levels in children 2 years after booster vaccination compared to prebooster levels (P < 0.05).