Table 2.
Numbers of IFN-γ-producing cells per 105 PBMCs 5 days after stimulation with PT, FHA, or Prn
| Vaccine and time of assessment | No. of cells and GMC after stimulation with: |
|||||
|---|---|---|---|---|---|---|
| PT |
FHA |
Prn |
||||
| n | GMC (95% CI) | n | GMC (95% CI) | n | GMC (95% CI) | |
| wP | ||||||
| Prebooster | 15 | 0.5 (0.2–1.6) | 14 | 4.4 (1.2–16) | 12 | 1.0 (0.2–3.8) |
| 28 days postbooster | 12 | 5.3 (1.1–27)a | 10 | 15.1 (2.9–79) | 11 | 7.3 (1.4–39) |
| 2 yr postbooster | 15 | 9.9 (2.2–45)a | 15 | 51 (16–163)a | 13 | 13 (2.4–74)a |
| aP | ||||||
| Prebooster | 13 | 18 (3.6–91) | 13 | 92 (22–374) | 13 | 27 (6.9–108) |
| 28 days postbooster | 11 | 7.0 (1.2–41) | 11 | 46 (10–215) | 11 | 6.0 (1.2–31) |
| 2 yr postbooster | 15 | 3.6 (1.1–12)b | 15 | 44 (21–94)b | 13 | 5.7 (2.1–15)b |
a
Significant increase postbooster compared to prebooster vaccination (P < 0.05).
b
Significant decrease postbooster compared to prebooster vaccination (P < 0.05).