Fig 5.

Identification of the apo-Fur box consensus sequence. The promoter regions of the four characterized H. pylori apo-Fur repressed genes, pfr, sodB, the cytochrome c₅₅₃ gene (c553), and hydA, were aligned (A), and a sequence logo (28) was generated (B). The logo is composed of stacks of letters, one for each position of the sequence. Sequence conservation at each position is indicated by the height of the letter stack (measured in bits). The apo-Fur box sequence(s) found in each promoter is colored in red. Other nearby promoter elements (−10 and −35 conserved sequences) are underlined. “comp” indicates that the complementary strand of DNA was used in the alignment. Designations of pfr I and pfr II are from the previously described protected regions (5).