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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Andrology. 2013 Sep 30;1(6):886–898. doi: 10.1111/j.2047-2927.2013.00126.x

Figure 2.

Figure 2

Increases in testis volume and weight suggest that combined hormone suppression and germ cell transplantation promote spermatogenic recovery. Testicular volume (expressed as a percentage of the pretreatment volume) (A) and testis weight at the end of the study, at 44 weeks after irradiation (B) are shown in radiation-only monkeys and monkeys that received GnRH-ant, for both the testes that did or did not receive transplantation at 8-weeks after irradiation. The shaded area represents the period of hormone suppression. Recovery of testis volume during the period from week 24 to week 44 and the testis weight at week 44 was compared between various groups, and significant (P<0.05) differences are shown by different letters, as follows: a: between the transplanted and sham-transplanted testes of GnRH-ant–treated monkeys (Wilcoxon test); b: between the transplanted and sham-transplanted testes of radiation-only monkeys (Wilcoxon test); c: between the transplanted testes of GnRH-ant–treated and radiation-only monkeys (Mann-Whitney test). The differences between the sham-transplanted testes of GnRH-ant–treated and radiation-only monkeys were not significant.