Table 1.
Regimen | RT with Cisplatin (n=18) |
RT with Cetuximab (n=29) |
p-value | ||
---|---|---|---|---|---|
Characteristic | No. | % | No. | % | |
Age (years) Median | 55 | 62 | 0.015 | ||
Range | 35–78 | 46–86 | |||
Sex | 0.32 | ||||
Male | 15 | 83.3 | 19 | 65.5 | |
Female | 3 | 16.7 | 10 | 34.5 | |
Race | 0.99 | ||||
Caucasian | 14 | 77.8 | 21 | 72.4 | |
African American | 3 | 16.7 | 6 | 20.7 | |
Native American | 1 | 5.6 | 2 | 6.9 | |
Smoking History | 0.94 | ||||
Yes | 14 | 77.8 | 26 | 89.7 | |
No | 4 | 22.2 | 3 | 10.3 | |
Insurance | 0.076 | ||||
Private | 5 | 27.8 | 4 | 13.8 | |
Medicare | 3 | 16.7 | 15 | 51.7 | |
Medicaid | 9 | 50.0 | 9 | 31.0 | |
None | 1 | 5.6 | 1 | 3.4 | |
ECOG performance status | 0.042 | ||||
0 | 11 | 61.1 | 8 | 27.6 | |
1 | 4 | 22.2 | 13 | 44.8 | |
2 | 3 | 16.7 | 6 | 20.7 | |
3 | 0 | 0.0 | 2 | 6.9 | |
ACE Comorbidity Index | 0.083 | ||||
0 (none) | 5 | 27.8 | 5 | 17.2 | |
1 (mild) | 7 | 38.9 | 8 | 27.6 | |
2 (moderate) | 4 | 22.2 | 5 | 17.2 | |
3 (severe) | 2 | 11.1 | 11 | 37.9 | |
Primary Site | 0.29 | ||||
Oropharynx | 10 | 55.6 | 13 | 44.8 | |
Oral Cavity | 0 | 0.0 | 3 | 10.3 | |
Larynx | 7 | 38.9 | 7 | 24.1 | |
Level II/III Neck Mass (Unknown Primary) | 1 | 5.6 | 2 | 6.9 | |
Hypopharynx | 0 | 0.0 | 4 | 13.8 | |
T Classification | 0.58 | ||||
T1 | 0 | 0.0 | 1 | 3.4 | |
T2 | 0 | 0.0 | 3 | 10.3 | |
T3 | 8 | 44.4 | 10 | 34.5 | |
T4 | 9 | 50.0 | 13 | 44.8 | |
Tx | 1 | 5.6 | 2 | 6.9 | |
N Classification | 0.66 | ||||
N0 & N1 | 6 | 33.3 | 12 | 41.4 | |
N2a-c | 11 | 61.1 | 15 | 51.7 | |
N3 | 1 | 5.6 | 2 | 6.9 | |
Overall Stage | 0.55 | ||||
III | 3 | 16.7 | 7 | 24.1 | |
IVa/IVb | 15 | 83.3 | 22 | 75.9 | |
HPV-Related | 0.99 | ||||
Oropharynx | 7 | 7 | |||
Level II/III neck mass (Unknown primary) | 1 | 1 | |||
Hypopharynx | 0 | 1 |