Table 5.

Neuro-QOL Item Bank Statistics

Domain	Sub-domain	Scoring direction	Item n tested	Testing sample	Item n calibrated (Uncalibrated)	Alpha	CFI	RMSEA	Slope range	Threshold range
Physical Health	Upper extremity function-Fine Motor, ADL	Better function	44	GP + C	20 (24)	0.97	0.949	0.115	2.11 to 4.68	−2.51 to −0.61
	Lower extremity function (Mobility)	Better function	37	GP + C	19 (18)	0.97	0.947	0.137	2.34 to 3.89	−3.23 to 0.39
	Fatigue	Severe symptom	20	C	19 (1)	0.99	0.942	0.192		−2.0 to 2.5
	Sleep disturbance	Severe symptom	20	C	8 (12)	0.85	0.946	0.091	1.57 to 2.89	−1.21 to 1.40
Emotional Health	Depression	Severe symptom	30	GP	24 (6)	0.98	0.966	0.098	2.42 to 5.79	−0.72 to 2.14
	Anxiety	Severe symptom	28	GP	21 (7)	0.96	0.935	0.112	1.40 to 5.52	−1.05 to 2.89
	Stigma	Severe symptom		C	24 (2)	0.95 + 0.93	0.939	0.096	1.49 to 4.19	−0.34 to 3.09
	Positive affect and well–Being	Lesser Symptom	27	GP	23 (4)	0.98	0.966	0.171	2.66 to 6.61	−1.89 to 1.47
	Emotional and behavioral dyscontrol	Severe symptom	20	C	18 (2)	0.95	0.895	0.115	2.52 to 3.52	−1.20 to 2.52
Cognitive Health	Applied cognition–general concerns	Better function	45	GP + C	18 (27)	0.94	0.938	0.098	1.80 to 4.53	−3.10 to 0.16
	Applied cognition–executive function	Better Function	45	GP + C	13 (32)	0.97	0.911	0.129	2.11 to 3.68	−4.22 to 0.05
Social Health	Ability to participate in social roles and activities	Better function	45	GP	45 (0)	0.95	0.943	0.224	2.32 to 6.38	−2.28 to 0.23
	Satisfaction with social roles and activities	Better Function	45	GP	45 (0)	0.92	0.945	0.232	2.67 to 6.74	−1.88 to 0.28

Testing sample: GP general population (wave lb), C clinical (wave la), GP + C combined general population plus subsequent clinical (wave 2)