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Change in biomarker [vascular endothelial growth factor (VEGF)-A, VEGF-C, interleukin-8 (IL-8) and soluble vascular endothelial growth factor receptor-3 (sVEGFR-3)] levels during treatment in the a sunitinib arm and b interferon-alpha arm. *P < 0.05; **P < 0.01; ***P < 0.0001 compared with baseline
