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. 2013 Nov;51(11):3484–3491. doi: 10.1128/JCM.00726-13

Table 1.

Clinical data at baseline of 3 groups with HBsAg seroclearance as determined by the Abbott Architect assay

Patient characteristic Data for group (n):
Spontaneous HBsAg loss (10) NA treated (8)a Acute hepatitis (8)
Age at first visit or medication (yr) 60.6 ± 12.6 46.8 ± 12.2 50.5 ± 10.8
Sex (no. of males/no. of females) 10/0 7/1 8/0
Route of infection (no. of vertical/no. of horizontal) 10/0 4/4 0/8
No. with genotype Aa/Ae/Ba/Bj/C 0/0/0/2/8 1/1/1/1/4 1/4/1/0/2
Clinical data
    ALT (median [range]) (IU/liter) 23.5 (8–51) 76 (11–220) 1,682 (455–3,622)
    HBeAg (no. positive/no. negative) 0/10 5/3 8/0
    HBV DNA (median [range]) (log copies/ml) 2.3 (<2.1 to 3.4) 7.4 (4.1 to >9.1) 6.5 (3.8–8.5)
    HBcrAg (median [range]) (log IU/ml) <3 (<3 to 3.3) 6.8 (4.2–8.6) 7.1 (6.6–8)
    Abbott Architect HBsAg-QT detection (median [range]) (mIU/ml) 1,300 (<50 to 10,880) 2,676,800 (9,680–89,679,600) 362,500 (91,200–40,000,000)
    NA therapy (no. with none/no. with LVD/no. with ETV)b 10/0/0 0/2/6 5/0/3
a

NA, nucleotide analogue.

b

LVD, lamivudine; ETV, entecavir.