Table 2.
Clinical data of spontaneous HBsAg loss patients at the last time point at which HBsAg was detectable by the Lumipulse HBsAg-HQ assay
| Clinical data | Values for patient no.: |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N1 | N2b | N3a,b | N4a,b | N5a,b | N6a,b | N7b | N8 | N9b | N10b | |
| Nucleotide analogue therapy | None | None | None | None | None | None | None | None | None | None |
| Age (yr) | 61 | 54 | 91 | 50 | 76 | 63 | 71 | 62 | 62 | 65 |
| HBeAg (+/−) | − | − | − | − | − | − | − | − | − | − |
| Abbott Architect HBsAg-QT detection (mIU/ml) | <50 | <50 | <50 | <50 | <50 | <50 | <50 | <50 | <50 | <50 |
| Lumipulse HBsAg-HQ detection (mIU/ml) | 8.0 | 51.0 | 12.0 | 8.9 | 10.4 | 5 | 5.8 | 20.4 | 11.7 | 30.3 |
| HBV DNA (log copies/ml) | Not detected | Not detected | <2.1 | <2.1 | 2.9 | 2.6 | <2.1 | Not detected | 2.7 | Not detected |
| HBcrAg (log IU/ml) | <3 | 3 | <3 | <3 | 3.2 | <3 | <3 | <3 | <3 | <3 |
| Anti-HBs (mIU/ml) | <10 | 973.8 | <10 | <10 | <10 | <10 | <10 | <10 | <10 | <10 |
a
Abbott Architect HBsAg-QT assay (IU/ml) was already negative at first visit.
b
Lumipulse HBsAg-HQ assay was still able to detect HBsAg at the last observation time.