Table 3.
Clinical data of NA-treated patients at the last time point at which HBsAg was detectable by the Lumipulse HBsAg-HQ assay
| Clinical data | Values for patient no.: |
|||||||
|---|---|---|---|---|---|---|---|---|
| L1 | L2 | E1 | E2 | E3 | E4a | E5 | E6 | |
| Nucleotide analogue therapy | LVD | LVD | ETV | ETV | ETV | ETV | ETV | ETV |
| Age (yr) | 62 | 49 | 53 | 40 | 44 | 44 | 67 | 39 |
| HBeAg (+/−) | − | − | − | − | − | − | − | − |
| Abbott Architect HBsAg-QT detection (mIU/ml) | 80b | <50 | <50 | <50 | 90b | <50 | 90b | <50 |
| Lumipulse HBsAg-HQ detection (mIU/ml) | 77.3 | 5 | 14.7 | 8 | 44.6 | 6.5 | 42.5 | 89 |
| HBV DNA (log copies/ml) | <2.1 | Not detected | Not detected | Not detected | 3.3 | 2.2 | <2.1 | Not detected |
| HBcrAg (log IU/ml) | <3 | 3.3 | 4.3 | 4.1 | 3.2 | <3 | 3.8 | 4.3 |
| Anti-HBs (mIU/ml) | <10 | <10 | <10 | <10 | <10 | <10 | <10 | <10 |
a
The Lumipulse HBsAg-HQ assay was still able to detect HBsAg at the last observation time.
b
HBsAg was detectable by both assays at this point, but HBsAg became undetectable at the next point.