Table 4.
Associations between HPV DNA detection in the two types of samples and cytological results
| Cytological resultsa | Sample | No. (%) of samples with HPV DNA detected using: |
No. (%) of samples with HPV infectiond | Crude odds ratio (95% CI) for detection results using: |
Crude odds ratio (95% CI) for HPV infectiond | ||||
|---|---|---|---|---|---|---|---|---|---|
| GP5+/GP6+ | MY09/11 | pU1M/2R | GP5+/GP6+ | MY09/11 | pU1M/2R | ||||
| Normal (n = 138) | Cervical | 49 (35.5) | 53 (38.4) | 50 (36.2) | 92 (66.7) | 1.0 | 1.0 | 1.0 | 1.0 |
| Urine | 44 (31.9) | 50 (36.2) | 36 (26.1) | 79 (57.2) | 1.0 | 1.0 | 1.0 | 1.0 | |
| ASCUS (n = 20) | Cervical | 13 (65.0) | 12 (60.0) | 10 (50.0) | 16 (80.0) | 3.4 (1.2–9.2)b | 2.4 (0.9–6.4) | 1.8 (0.7–4.6) | 2.0 (0.6–6.4) |
| Urine | 9 (45.0) | 10 (50.0) | 7 (35.0) | 15 (75.0) | 1.7 (0.7–4.6) | 1.8 (0.7–4.6) | 1.5 (0.6–4.1) | 2.2 (0.8–6.6) | |
| LSIL (n = 32) | Cervical | 19 (59.4) | 21 (65.6) | 17 (53.1) | 25 (78.1) | 2.7 (1.2–5.9)b | 3.1 (1.3–7.0)b | 2.0 (0.9–4.4) | 1.8 (0.7–4.5) |
| Urine | 14 (43.8) | 11 (34.4) | 16 (50.0) | 27 (84.4) | 1.7 (0.8–3.7) | 0.9 (0.4–2.1) | 2.8 (1.3–6.4)b | 4.0 (1.4–11.4)b | |
| HSIL (n = 4) | Cervical | 3 (75.0) | 0 (0.0) | 2 (50.0) | 3 (75.0) | 5.4 (0.5–55.4) | 0.0 (NC)c | 1.8 (0.2–13.0) | 1.5 (0.2–14.9) |
| Urine | 1 (25.0) | 1 (25.0) | 2 (50.0) | 3 (75.0) | 0.7 (0.1–7.1) | 0.6 (0.1–5.8) | 2.8 (0.4–21.2) | 2.2 (0.2–22.4) | |
a
ASCUS, atypical squamous cells of undetermined significance; HSIL, high-grade squamous intraepithelial lesion; LSIL, low-grade squamous intraepithelial lesion.
b
Statistically significant.
c
NC, not calculable. The estimator could not be calculated because one of the fields contained no data during the dispersion analysis.
d
HPV infection was considered positive when the PCR results using any of the three primer sets were positive.