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Application of the I-C test to characterize carbapenemase-producing (black bars) and carbapenemase-negative strains (gray bars). The difference (Δd) between the zone diameters around imipenem disks supplemented or not with cloxacillin at 1,000 (A), 2,000 (B), 3,000 (C), or 4,000 μg (D) per disk is indicated in millimeters. The dashed line indicates the finally chosen cutoff point.
